Coagulopathy correlates with muscle titin injury in critically ill patients
Authors' conclusion
Coagulopathy correlated with muscle titin fragmentation, as an independent risk factor.
Study context
- Population
- Critically ill patients
- Participants
- 111 patients
- Comparison
- JAAM-DIC vs no JAAM-DIC
- Primary endpoint
- Mean N-titin/Cre measured on days 1, 3, 5 and 7
Primary result
As reported in the abstract
Mean N-titin/Cre
- Mean N-titin/Cre significantly higher in the JAAM-DIC group
- JAAM-DIC an independent risk factor for mean N-titin/Cre in multivariable analysis; other severity scores were not
Original publication
Coagulopathy correlates with muscle titin injury in critically ill patients. J Crit Care. Published 22 December 2022. doi:10. 1016/ j. jcrc. 2022. 154234
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