ICU sedation, delirium & recovery

Cognitive Functioning After Circulatory Shock: A Prospective Observational Study

Acta Anaesthesiol ScandPublished Prospective observational study

Authors' conclusion

We found cognitive impairment in more than three out of four ICU survivors immediately after ICU treatment for circulatory shock. We observed an improvement in cognitive functioning between ICU discharge and 3 months follow-up.

Study context

Population
Adult intensive care unit (ICU) survivors of circulatory shock, Helsinki University Hospital ICU36 completed 3-month follow-up
Participants
55 vs 48
Exposure
Patients vs Controls
  • Patientsn = 55
  • Controlsn = 48reference
Outcome
Cognitive functioning (Montreal Cognitive Assessment (MoCA) test; cognitive impairment = MoCA score < 26 points)
Follow-up
Within 3 days of ICU discharge and 3 months thereafter
Methodological detailspreplanned sub-study of the ASSESS-SHOCK study, single-centre
  • Preplanned sub-study of the ASSESS-SHOCK study
  • Single-centre

Main finding

As reported in the abstract

MoCA score and prevalence of cognitive impairment
OutcomeControls
MoCA score and prevalence of cognitive impairmentmedian 27 (IQR 25–28) points
Prevalence of cognitive impairment33%
  • Patients (3 months) vs Patients (at discharge): P < 0.001 — improvement from discharge to follow-up

Observational data: associations, not effects.

Original publication

Cognitive Functioning After Circulatory Shock: A Prospective Observational Study. Acta Anaesthesiol Scand. Published 7 May 2026. doi:10.1111/aas.70250

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