Cardiac arrest & resuscitation

Cognitive impairment and psychopathology in sudden out-of-hospital cardiac arrest survivors: Results from the REVIVAL cohort study

ResuscitationPublished Prospective cohort study

Authors' conclusion

OHCA survivors exhibited both cognitive impairment and symptoms of psychopathology during hospitalisation comparable to previous studies, which were associated with unfavorable mental health outcomes at three-month follow-up.

Study context

Population
Out-of-hospital cardiac arrest (OHCA) survivors
Participants
297 survivors
Outcome
Cognitive impairment (Montreal Cognitive Assessment (MoCA)) and symptoms of anxiety, depression (Hospital Anxiety and Depression Scale (HADS)) and traumatic distress (Impact of Event Scale-revised (IES-R)) during hospitalisation, and their evolution at follow-up
Follow-up
hospitalisation and three-month follow-up
Methodological detailsmulticentre
  • Multicentre

Main finding

As reported in the abstract

Prevalence during hospitalisation · hospitalisation

Cognitive impairment

65%

Symptoms of anxiety

25%

Symptoms of depression

20%

Symptoms of traumatic distress

21%

Observational data: associations, not effects.

Further findings

Association of in-hospital screening result with unfavourable outcome at follow-up · three-month follow-up

OR (95% CI)P value
Cognitive impairment during hospitalisationUnfavourable cognitive outcome · logistic regression2.55 (1.36–4.75)P = 0.02
Anxiety during hospitalisationAnxiety at follow-up · logistic regression6.70 (2.40–18.72)P < 0.001
Depression during hospitalisationDepression at follow-up · logistic regression4.69 (1.69–13.02)P < 0.001
Traumatic distress during hospitalisationTraumatic distress at follow-up · logistic regression7.07 (2.67–18.73)P < 0.001

Prevalence at follow-up · three-month follow-up

Cognitive impairment
53%
Symptoms of anxiety
17%
Symptoms of depression
15%
Symptoms of traumatic distress
19%

Original publication

Cognitive impairment and psychopathology in sudden out-of-hospital cardiac arrest survivors: Results from the REVIVAL cohort study. Resuscitation. Published 4 October 2023. doi:10.1016/j.resuscitation.2023.109984

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