Neuroanaesthesia & neurocritical care
Comparative analysis of two standardised protocols for prevention of vasospasm following aneurysmal subarachnoid haemorrhage: A retrospective pilot study
Authors' conclusion
New therapy bundle has the potential to be more effective than the standard therapy method.
Study context
- Population
- Patients with aneurysmal SAH, Barmherzige Brüder hospital, Regensburg, Germany, 2015–2022; excluding severe liver, blood or kidney disease
- Participants
- 44 matched pairs
- Exposure
- New therapy bundle vs previous standard therapy
- Group 1n = 22
- Group 2n = 22reference
- Outcome
- Incidence of vasospasm, survival and clinical outcome
Methodological detailssingle-centre, matched pairs
- Single-centre
- Matched pairs
Main finding
As reported in the abstract
Incidence of vasospasm, survival and clinical outcome (GOS)
- No significant difference in incidence of vasospasm
- No significant difference in number of surviving patients
- No significant difference in clinical outcome (GOS after hospitalisation)
- Group 1 vs Group 2: P = 0.34
Observational data: associations, not effects.
Further findings
Hospital LOS · significantly shorter in group 1
P = 0.004
ICU LOS · significantly shorter in group 1
P = 0.012
Original publication
Comparative analysis of two standardised protocols for prevention of vasospasm following aneurysmal subarachnoid haemorrhage: A retrospective pilot study. Eur J Anaesthesiol Intensive Care. Published 9 May 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →