Neuroanesthesia & neurocritical care
Comparative Effectiveness of Intracranial Pressure Monitoring on 6-Month Outcomes of Critically Ill Patients With Traumatic Brain Injury
Authors' conclusion
In this cohort study, ICP monitoring was associated with poorer recovery and more frequent medical interventions with their relevant adverse effects.
Study context
- Population
- Patients with traumatic brain injury (TBI) meeting Brain Trauma Foundation guidelines for intracranial pressure (ICP) monitoring, 43 intensive care units (ICUs) in Italy and Hungary (CREACTIVE Consortium)
- Participants
- 1,448 patients · 43 ICUs
- Exposure
- Monitored vs Nonmonitored
- Monitoredn = 503
- Nonmonitoredn = 945reference
- Outcome
- Functional disability (Glasgow Outcome Scale-Extended (GOS-E) score)
- Follow-up
- 6 months
Methodological detailspropensity score-matched, multicentre
- Propensity score-matched
- Multicentre
Main finding
As reported in the abstract
GOS-E categories at 6 months (matched)
Death/vegetative state
Severe disability
Moderate disability
Good recovery
- Monitored vs Nonmonitored: P = 0.005 — worse 6-month recovery in monitored patients
Observational data: associations, not effects.
Further findings
- Monitored patients received medical therapies significantly more frequently
Original publication
Comparative Effectiveness of Intracranial Pressure Monitoring on 6-Month Outcomes of Critically Ill Patients With Traumatic Brain Injury. JAMA Netw Open. Published 5 September 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →