Perioperative medicine & outcomes
Comparison of 6-min walk test distance vs. estimated maximum oxygen consumption for predicting postoperative pulmonary complications in patients undergoing upper abdominal surgery: a prospective cohort study
Main finding · AUC for predicting PPCsResult — go to the resultNRI 0.272 95% CI 0.130–0.406Authors' conclusion
The results suggested that e[Formula: see text]O2max calculated from the 6MWT is a better predictor of PPCs than 6MWD in patients undergoing upper abdominal surgery
Study context
- Population
- Adults scheduled for elective major upper abdominal surgery, March 2019 to May 2021
- Participants
- 308 adults · 71 developed postoperative pulmonary complications (PPCs)
- Exposure
- eVO2max vs 6MWD for predicting PPCs
- Outcome
- AUC of 6MWD and eVO2max in predicting PPCs
Methodological detailssingle-centre, diagnostic accuracy, Patients unable to complete the 6MWT or taking beta-blockers excluded
- Single-centre
- Diagnostic accuracy
- Patients unable to complete the 6MWT or taking beta-blockers excluded
Main finding
AUC for predicting PPCs
Net reclassification index (NRI)
0.272
95% CI 0.130–0.406
By group
6MWD
- AUC
- 0.758 (95% CI 0.694-0.822)
- Optimum cutoff
- 372.5 m
- Sensitivity
- 63.4%
- Specificity
- 79.3%
e[Formula: see text]O2max
- AUC
- 0.912 (95% CI 0.875-0.949)
- Optimum cutoff
- 30.8 ml/kg/min
- Sensitivity
- 91.6%
- Specificity
- 79.3%
AUC
6MWD0.758 (95% CI 0.694-0.822)
e[Formula: see text]O2max0.912 (95% CI 0.875-0.949)
Optimum cutoff
6MWD372.5 m
e[Formula: see text]O2max30.8 ml/kg/min
Sensitivity
6MWD63.4%
e[Formula: see text]O2max91.6%
Specificity
6MWD79.3%
e[Formula: see text]O2max79.3%
As reported in the abstract
Observational data: associations, not effects.
Further findings
| Outcome | NRI (95% CI) |
|---|---|
| Net reclassification index (NRI)eVO2max vs 6MWT | 0.272 (0.130–0.406) |
Original publication
Comparison of 6-min walk test distance vs. estimated maximum oxygen consumption for predicting postoperative pulmonary complications in patients undergoing upper abdominal surgery: a prospective cohort study. Perioper Med (Lond). Published 23 May 2023. doi:10.
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