Paediatric anaesthesia & critical care
Routine Replacement of Fasting Deficits in Pediatric Ambulatory Anesthesia: A Propensity‐Matched Retrospective Cohort Study
Main finding · Intraoperative vasopressor administrationResult — go to the resultAdjusted odds ratio 1.13 95% CI 0.92–1.38Authors' conclusion
In children undergoing ambulatory procedures, a substantial reduction in routine fasting-deficit replacement was not associated with increased vasopressor use, and no important differences were observed in early postoperative recovery.
Study context
- Population
- Children undergoing ambulatory procedures at a tertiary children's hospital, May 2024-March 20258,508 after matching
- Participants
- 9,640 children
- Exposure
- Reduced vs routine fasting-deficit replacement
- Reduced fluid administrationn = 4,254
- Routine replacementn = 4,254reference
- Outcome
- Intraoperative vasopressor administration
Methodological detailspropensity score matched, single-centre, natural experiment
- Propensity score matched
- Single-centre
- Natural experiment
Main finding
As reported in the abstract
Adjusted odds ratio
1.13
95% CI 0.92–1.38
Reduced fluid administration vs Routine replacement
aOR 1.13 (95% CI 0.92–1.38)
Observational data: associations, not effects.
Secondary outcomes
Mean intraoperative crystalloid administration
- Decreased following the practice change
- 38.1%
Post-anesthesia care unit (PACU) rescue antiemetic use
- Did not differ between groups
- aOR 0.44 (95% CI 0.13-1.43)
- Low event rates; not powered for this outcome
PACU LOS
- Did not differ between groups (mean difference, min)
- −0.7
- Not powered for this outcome
ED encounters within 24 h
- Did not differ between groups
- aOR 0.53 (95% CI 0.21-1.32)
- Low event rates; not powered for this outcome
Original publication
Routine Replacement of Fasting Deficits in Pediatric Ambulatory Anesthesia: A Propensity‐Matched Retrospective Cohort Study. Paediatr Anaesth. Published 13 July 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →