Hemodynamics, fluids & transfusion
Comparison Between Changes in Systolic-Pressure Variation and Pulse-Pressure Variation After Passive Leg Raising to Predict Fluid Responsiveness in Postoperative Critically Ill Patients
Authors' conclusion
ΔSPVPLR and ΔPPVPLR could accurately predict fluid responsiveness in postoperative critically ill patients. There was no difference in the ability to predict fluid responsiveness between ΔSPVPLR and ΔPPVPLR.
Study context
- Population
- Postoperative critically ill patients with acute circulatory failure in a surgical ICU of a tertiary hospital38 responders · 36 nonresponders
- Participants
- 74 patients
- Comparison
- ΔSPVPLR vs ΔPPVPLR to predict fluid responsiveness
- Outcome
- Prediction of fluid responsiveness (stroke volume increase ≥10% after PLR, by transthoracic echocardiography)
Methodological detailsprospective observational, single-centre
- Prospective observational
- Single-centre
Performance
As reported in the abstract
Prediction of fluid responsiveness
| Test or model | AUC | Optimal cutoff | Gray zone | Patients in gray zone |
|---|---|---|---|---|
| ΔPPVPLR | 0.917 | 2.3% | 1.6% to 3.3% | 19 (25.7%) |
| ΔSPVPLR | 0.908 | 1.9% | 1.1% to 2.0% | 18 (24.3%) |
AUC
ΔPPVPLR0.917
ΔSPVPLR0.908
Optimal cutoff
ΔPPVPLR2.3%
ΔSPVPLR1.9%
Gray zone
ΔPPVPLR1.6% to 3.3%
ΔSPVPLR1.1% to 2.0%
Patients in gray zone
ΔPPVPLR19 (25.7%)
ΔSPVPLR18 (24.3%)
- ΔPPVPLR vs ΔSPVPLR: P = 0.805 — no notable distinction
Original publication
Comparison Between Changes in Systolic-Pressure Variation and Pulse-Pressure Variation After Passive Leg Raising to Predict Fluid Responsiveness in Postoperative Critically Ill Patients. J Cardiothorac Vasc Anesth. Published 17 November 2023. doi:10.
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