Hemodynamics, fluids & transfusion

Comparison between invasive radial and femoral arterial pressures and carotid tonometry in intensive care unit (ICU) patients: A physiological study

Ann Intensive CarePublished Prospective observational physiological study

Authors' conclusion

The pressure amplification was lower at the femoral than radial artery level and should not be neglected in ICU patients when interpreting arterial pressures and estimating hemodynamic variables.

Study context

Population
Consecutive spontaneously breathing ICU patients already equipped with an arterial catheter
Participants
98 participants
Exposure
Radial vs Femoral
  • Radialn = 59
  • Femoraln = 39reference
Outcome
Difference in pulse pressure amplification (PPAMP) and systolic pressure amplification (SPAMP) between femoral and radial arteries (vs carotid tonometry as surrogate of aortic pressure)
Methodological detailssingle-center
  • Single-center

Main finding

As reported in the abstract

PPAMP and SPAMP

P = 0.04

PP ratio higher at radial than femoral level
P = 0.03
SP ratio higher at radial than femoral level
P = 0.04

Observational data: associations, not effects.

Secondary outcomes

Overestimation of centrally-derived cardiac power output (CPO)

P = 0.04

Overestimation of centrally-derived cardiac power output (CPO) — Correlation of overestimation with pulse pressure amplification (PPAMP) and systolic pressure amplification (SPAMP) (r)
0.85
Overestimation of centrally-derived cardiac power output (CPO) — Correlation of overestimation with PP ratio (r)
0.77
Overestimation of centrally-derived cardiac power output (CPO) — Correlation of overestimation with SP ratio (r)
0.85
  • Overestimation of centrally-derived cardiac power output (CPO): all p < 0.001

Peripheral vs carotid SAP and PP

Femoral and radial SAP and PP higher than carotid SAP and PP
P < 0.001

Total arterial stiffness and effective arterial elastance (Ea)

Similar results to CPO

Original publication

Comparison between invasive radial and femoral arterial pressures and carotid tonometry in ICU patients: A physiological study. Ann Intensive Care. Published 27 April 2026. doi:10.1016/j.aicoj.2026.100068

Composed by AI from the published abstract and checked against it. How Briefs are made →

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