Comparison between ultrasound-guided intertransverse process and erector spinae plane blocks for breast cancer surgery: A randomised controlled trial
Primary result · Blocked dermatomes at anterior T2-7Result — go to the resultMedian difference 4 95% CI 3–4Authors' conclusion
Although ITPB demonstrated more consistent anterior dermatomal spread and improved immediate postoperative analgesia compared to ESPB, no additional benefits were identified for breast cancer surgery.
Study context
- Population
- Females undergoing unilateral breast cancer surgery, tertiary hospital in China, 20 February to 31 July 2023
- Participants
- 68 females
- Comparison
- Ultrasound-guided intertransverse process block (ITPB) at T2-6 vs erector spinae plane block (ESPB) at T4
- Primary endpoint
- Number of blocked dermatomes at anterior T2-7 (predefined superiority margin 1.5 dermatomes)
- Follow-up
- 45 min after block completion
Methodological detailsblinded, active-controlled, superiority, GA and postoperative analgesia standardised
- Blinded
- Active-controlled
- Superiority
- GA and postoperative analgesia standardised
Primary result
Blocked dermatomes at anterior T2-7
Median difference
4
95% CI 3–4
P < 0.001
By group
ITPB vs ESPB
median difference 4 (95% CI 3–4); P < 0.001
As reported in the abstract
Secondary outcomes
Median
| Outcome | ITPB | ESPB | Median difference (95% CI) | P value | |
|---|---|---|---|---|---|
| Worst resting pain score (11-point NRS) within 30 min in the recovery room (gatekeeping-tested)Tested following a gatekeeping procedure | 1 (IQR 0–2) | 3 (IQR 1–4) | −1 (−2 to 0) | P = 0.004 | |
| −3−2−101Difference (linear scale) |
Rescue analgesics within 30 min in the recovery room
- Fewer rescue analgesics required in the ITPB vs ESPB group
Other secondary outcomes (resting pain scores, opioid consumption, satisfaction, recovery quality, adverse effects within 24 h) · within 24 h postoperatively
- No other clinically relevant results observed
Original publication
Comparison between ultrasound-guided intertransverse process and erector spinae plane blocks for breast cancer surgery: A randomised controlled trial. Eur J Anaesthesiol. Published 29 October 2024. doi:10.
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