Comparison of adductor pollicis and flexor hallucis brevis muscle electromyographic responses: a prospective cohort study
Main finding · Onset time of NMB (TOF count 0)Result — go to the resultMean paired difference 31 sec 95% CI 5–56Authors' conclusion
While quantitative neuromuscular monitoring at the flexor hallucis brevis (foot) muscle showed some statistical differences in onset time and a recovery compared with monitoring at the adductor pollicis muscle (hand), these differences are of unclear clinical significance.
Study context
- Population
- Patients receiving intraoperative NMB managed at the attending anesthesiologists' discretion, with sugammadex recovery81 with simultaneous onset data
- Participants
- 103 patients
- Exposure
- Foot vs Hand
- Outcome
- Onset time of neuromuscular blockade (TOF count 0) at the two sites
Methodological detailssimultaneous paired measurements
- Simultaneous paired measurements
Main finding
Onset time of NMB (TOF count 0)
Mean paired difference
31 sec
95% CI 5–56
P = 0.02
Quantitative neuromuscular monitoring at flexor hallucis brevis (foot) vs adductor pollicis (hand)
mean paired difference 31 sec (95% CI 5–56); P = 0.02
As reported in the abstract
Observational data: associations, not effects.
Further findings
Offset time (sugammadex recovery to train-of-four (TOF) ratio ≥ 0.9)
| Mean paired difference (sec) (95% CI) | P value | ||
|---|---|---|---|
| The two sites | −3 (−56 to 50) | P = 0.26 | |
| −100−50050100Difference, sec (linear scale) |
Original publication
Comparison of adductor pollicis and flexor hallucis brevis muscle electromyographic responses: a prospective cohort study. Can J Anaesth. Published 1 August 2025. doi:10.
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