ICU sedation, delirium & recovery
Comparison of methods to normalize urine output in critically ill patients: a multicenter cohort study
Authors' conclusion
UO normalization by IBW lead to a stable incidence of oliguria across categories of weight and improved the association between oliguria and outcomes.
Study context
- Population
- Adult ICU patients (Swiss derivation cohort; US MIMIC-IV validation cohort), excluding maintenance hemodialysis, declined consent or < 6 consecutive urine output (UO) measurements15,322 derivation, 28,610 validation
- Exposure
- UO normalized by ideal body weight (IBW) vs actual body weight (ABW)
- Outcome
- Oliguria incidence and association with 90-day mortality and AKD at hospital discharge, by UO normalization method
Methodological detailsderivation and validation cohorts
- Derivation and validation cohorts
Main finding
As reported in the abstract
Proportion of patients correctly classified
Correctly classified, 90-day mortality: ABW vs IBW
37.6 to 48.3%
Correctly classified, acute kidney disease (AKD): ABW vs IBW
37.8 to 47%
Observational data: associations, not effects.
Further findings
- Best UO predictor was IBW
Original publication
Comparison of methods to normalize urine output in critically ill patients: a multicenter cohort study. Crit Care. Published 19 December 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →