Perioperative medicine & outcomes
Comparison Over Two Eras of Perioperative Adverse Outcomes in Children With and Without Congenital Heart Disease Undergoing Noncardiac Surgery
Authors' conclusion
These findings demonstrate meaningful improvements in postoperative outcomes over time, notably reduced rates of 30-day mortality, reintubation, and readmission in the non-CHD group. Patients with minor and major CHD experienced significant declines in reintubation and readmission, while those with severe CHD showed reduced reintubation.
Study context
- Population
- Children undergoing noncardiac surgery, 2012–2022 (excluding 2020), with and without congenital heart disease (CHD)11.7% with CHD
- Participants
- 1,023,638 children
- Exposure
- Era 2017-2022 vs 2012-2016, by CHD severity
- Outcome
- Adverse outcomes: 30-day mortality, cardiac arrest, reintubation, reoperation, readmission
- Follow-up
- 30 days
Methodological detailsACS-NSQIP Pediatric database, multivariable logistic regression
- ACS-NSQIP Pediatric database
- Multivariable logistic regression
Main finding
As reported in the abstract
Adverse outcomes, later vs earlier era, by CHD severity · 30-day
Most consistent improvement in reintubation, including severe CHD
0.69
aOR; 95% CI: 0.53, 0.89p = 0.005
Observational data: associations, not effects.
Original publication
Comparison Over Two Eras of Perioperative Adverse Outcomes in Children With and Without Congenital Heart Disease Undergoing Noncardiac Surgery. Paediatr Anaesth. Published 26 August 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →