Perioperative medicine & outcomes

Comparison of societal guidance on perioperative management of glucagon-like peptide-1 receptor agonists: implications for clinical practice and future investigations

Can J AnaesthPublished Narrative review comparing society guidance

Authors' conclusion

Society-endorsed statements and guidelines provide varying recommendations on the perioperative management of GLP-1 RAs.

Study context

Population
Society-endorsed statements and guidelines on perioperative management of GLP-1 receptor agonists
Participants
14 society statements
Outcome
Variation in society guidance
Methodological detailsinternet search of society-endorsed statements and guidelines, top 20 countries by anesthesiology society membership (World Federation of Societies of Anesthesiologists), English only
  • Internet search of society-endorsed statements and guidelines
  • Top 20 countries by anesthesiology society membership (World Federation of Societies of Anesthesiologists)
  • English only

Main finding

As reported in the abstract

  • Endorsed statements from 14 major anesthesiology, endocrinology and gastroenterology societies
  • Considerable variation in recommendations: withholding before surgery and its duration, avoiding deep sedation or GA, RSI use, prolonged fasting and clear fluid before nil per os, recognition of aspiration-risk signs and symptoms, perioperative glucose management, POCUS for risk assessment

Original publication

Comparison of societal guidance on perioperative management of glucagon-like peptide-1 receptor agonists: implications for clinical practice and future investigations. Can J Anaesth. Published 26 August 2024. doi:10.1007/s12630-024-02810-5

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