Comparison of surgical pleth index-guided analgesia versus conventional analgesia technique in general anesthesia surgeries: A systematic review and meta-analysis
Pooled resultResult — go to the resultSMD 0.16 95 % CI −0.15 to 0.47Authors' conclusion
Compared to the conventional analgesia group, SPI-guided analgesia does not reduce intraoperative opioid consumption in adult patients undergoing general anesthesia.
Study context
- Population
- Adults undergoing GA14 studies
- Comparison
- Surgical pleth index (SPI)-guided analgesia vs conventional analgesia
- Outcome
- Intraoperative opioid consumption
Pooled result
As reported in the abstract
SMD
0.16
95 % CI −0.15 to 0.47
P = 0.33
SPI-guided analgesia vs Control
SMD 0.16 (95 % CI −0.15 to 0.47); P = 0.33
Further pooled results
| Outcome | Estimate | P value | |
|---|---|---|---|
| Intraoperative propofol dosage | SMD −0.31 (95 % CI −0.54 to −0.08) | P = 0.008 | |
| Eye-opening time | WMD −1.89 (95 % CI −2.47 to −1.31) | P < 0.001 | |
| −3−2−101Difference (linear scale) |
| Outcome | RR (95 % CI) | P value | |
|---|---|---|---|
| Intraoperative tachycardia | 0.50 (0.30–0.85) | P = 0.011 | |
| 0.20.5125Relative risk (log scale) |
Extubation time, pain scores, postoperative opioid consumption
- No statistically significant differences
Safety
PONV
- No statistically significant difference
Original publication
Comparison of surgical pleth index-guided analgesia versus conventional analgesia technique in general anesthesia surgeries: A systematic review and meta-analysis. J Clin Anesth. Published 28 February 2025. doi:10.
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