The use of the surgical pleth index to guide anaesthesia in gastroenterological surgery: a randomised controlled study
Authors' conclusion
The use of SPI guidance for the administration of remifentanil during surgery did not help to reduce the remifentanil consumption.
Study context
- Population
- Patients aged 50 years and older scheduled for major abdominal surgery
- Participants
- 80 patients
- Comparison
- Surgical Pleth Index (SPI)-guided vs clinically guided remifentanil administration
- Primary endpoint
- Intraoperative remifentanil consumption
Primary result
As reported in the abstract
- No difference in intraoperative remifentanil consumption (4.5 µg kg- 1h- 1 vs. 5.6 µg kg- 1h- 1; the abstract does not say which value belongs to which group)
- p = 0.14
Further findings
| Outcome | P value |
|---|---|
| Proportion of hypotensive time (MAP < 65)No difference (3.7% vs. 1.6%) | P = 0.40 |
| Severe hypotension (MAP < 55), invasive BP monitoring subgroup0.3% vs. 0.0%; less in the treatment group · subgroup | P = 0.02 |
| Intermediate hypotension (MAP < 65), invasive BP monitoring subgroup10.2% vs. 2.6%; less in the treatment group · subgroup | P = 0.07 |
| Remifentanil consumption, invasive BP monitoring subgroupSubgroup | P = 0.03 |
- Remifentanil consumption, invasive BP monitoring subgroup: 3.5 µg kg- 1h- 1 vs. 5.1 µg kg- 1h- 1; higher in the treatment group
Original publication
The use of the surgical pleth index to guide anaesthesia in gastroenterological surgery: a randomised controlled study. J Clin Monit Comput. Published 20 January 2025. doi:10.
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