Respiratory failure & ventilation

Computed Tomography Yield and Predictors of Pulmonary Embolism in Mechanically Ventilated Patients—A Retrospective Study

Acta Anaesthesiol ScandPublished Retrospective cohort study

Authors' conclusion

The diagnostic yield of clinical CTPA exams for suspected PE in mechanically ventilated patients fell within a range commonly cited for suspected acute PE in emergency department populations, but its association with clinical signs described in the CTPA order and with selected patient variables was low.

Study context

Population
Adult mechanically ventilated ICU patients undergoing computed tomography pulmonary angiography (CTPA) on clinical PE suspicionCTPA exams of 1113 thoracic CT
Participants
243 participants
Outcome
Diagnostic yield (rate of positive CTPA exams) for suspected PE
Methodological detailstwo ICUs, 5-year period, multivariable logistic regression
  • Two ICUs
  • 5-year period
  • Multivariable logistic regression

Main finding

As reported in the abstract

Positive CTPA (yield)

Positive CTPA exams

52 (21% [95% CI: 17-26])

Observational data: associations, not effects.

Further findings

Predictors of a positive CTPA

Order reasons "Elevated D-dimer" and "Undefined clinical suspicion" significantly associated with a positive exam
No selected patient variable significantly associated with PE on CTPA

Original publication

Computed Tomography Yield and Predictors of Pulmonary Embolism in Mechanically Ventilated Patients—A Retrospective Study. Acta Anaesthesiol Scand. Published 8 March 2026. doi:10.1111/aas.70216

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