Contemporary Rationale for Delivering Enteral Nutrition in Critically Ill Adults
Authors' conclusion
Contemporary data support the use of restrictive dose enteral nutrition during the acute phase of critical illness. High-dose protein is not superior to lower and is associated with worse outcomes in critically ill adults with acute kidney injury and those with greater severity of illness.
Study context
- Population
- Critically ill adults
- Comparison
- Restrictive vs full-dose enteral nutrition; high-dose vs standard protein
Main finding
As reported in the abstract
- Restrictive-dose enteral nutrition during the acute phase preserves gut integrity, supports the microbiome and modulates immune dysregulation
- Full-dose vs restrictive-dose enteral nutrition in the acute phase may offset the benefit of enteral feeding, causing iatrogenic stresses leading to worse outcomes (contemporary RCTs)
- High-dose vs standard protein does not improve clinical outcomes and may be harmful in certain subsets
Original publication
Contemporary Rationale for Delivering Enteral Nutrition in Critically Ill Adults. Crit Care Med. Published 21 May 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →