Respiratory failure & ventilation

COVID-19 does not influence functional status after ARDS therapy

Crit CarePublished Secondary analysis of a randomised multicentre trial

Authors' conclusion

Resolution of organ dysfunction within the first 5 days significantly impacts long-term morbidity. Acute respiratory distress syndrome caused by COVID-19 was not associated with increased mortality or morbidity.

Study context

Population
Patients with ARDS caused by COVID-19 or of other origin
Participants
144 patients
Comparison
COVID-19 ARDS vs ARDS of other origin

Primary result

As reported in the abstract

Mortality and Barthel index impairment · up to 180 days
  • Mortality after 180 days and impairment measured by the Barthel index did not differ between patients with and without COVID-19

Further findings

Risk factors for high disability (binary logistic regression)

SOFA score at day 5 an independent risk factor for high disability in both groups
SOFA score dynamic within the first 5 days significantly impacted disability in the non-COVID group

Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.

Original publication

COVID-19 does not influence functional status after ARDS therapy. Crit Care. Published 5 February 2023. doi:10.1186/s13054-023-04330-y

Composed by AI from the published abstract and checked against it. How Briefs are made →

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