Regional anesthesia

Craniocaudal spread and clinical translation for combined erector spinae plane block and retrolaminar block in soft embalmed cadavers: a randomised controlled equivalence study

Br J AnaesthPublished Randomised controlled equivalence study

Primary resultResult — go to the resultDifference −0.1 90% CI −1.4 to 1.6

Authors' conclusion

Combined ESP and RL injections showed equivalent and consistent spread at T3 and T6 injection sites.

Study context

Population
Prone soft embalmed Thiel cadaversinjections in 10 cadavers
Participants
20 participants
Comparison
Combined erector spinae plane (ESP) + retrolaminar (RL) injection at T3 vs T6
Primary endpoint
Craniocaudal dye spread (vertebral levels) after combined ESP and RL injection with a 19 G Tuohy needle
Methodological detailssoft embalmed Thiel cadavers, single anaesthetist, 10 ml dye onto transverse process, then 10 ml onto laminae; 3-8 MHz transducer, paramedian sagittal plane; dissection 24 h later
  • Soft embalmed Thiel cadavers
  • Single anaesthetist
  • 10 ml dye onto transverse process, then 10 ml onto laminae; 3-8 MHz transducer, paramedian sagittal plane; dissection 24 h later

Primary result

As reported in the abstract

Difference

−0.1

90% CI −1.4 to 1.6

P = 0.904

By group

T3 vs T6
difference −0.1 (90% CI −1.4 to 1.6); P = 0.904

Further findings

Direction of dye spread

Dye extended uniformly, cranially and caudally, from the point of injection

Clinical translation: combined ESP and RL block before mastectomy (6 patients)

Extensive anterior, lateral, and posterior chest wall paraesthesia over 4 to 6 dermatomes
  • Pilot study

Original publication

Craniocaudal spread and clinical translation for combined erector spinae plane block and retrolaminar block in soft embalmed cadavers: a randomised controlled equivalence study. Br J Anaesth. Published 9 February 2024. doi:10.1016/j.bja.2024.01.017

Composed by AI from the published abstract and checked against it. How Briefs are made →

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