Cardiothoracic & vascular anesthesia

Criteria for continuous neuraxial analgesia associated with reduced mortality in patients undergoing thoracotomy

Reg Anesth Pain MedPublished Retrospective cohort study

Main finding · All-cause inpatient mortalityResult — go to the resultOdds ratio 0.49 95 % CI 0.237–1.12

Authors' conclusion

Neuraxial analgesic techniques are associated with reductions in postoperative mortality after open thoracic surgery in selected patients.

Study context

Population
Patients undergoing open thoracotomy
Participants
1,620 patients
Exposure
Continuous neuraxial analgesia vs no neuraxial analgesia
  • Neuraxialn = 796
  • No neuraxialn = 824reference
Outcome
All-cause inpatient mortality
Methodological detailsmulticentre registry (German Thoracic Registry, 4 university hospitals), multivariable logistic regression
  • Multicentre registry (German Thoracic Registry, 4 university hospitals)
  • Multivariable logistic regression

Main finding

As reported in the abstract

Odds ratio

0.49

95 % CI 0.237–1.12

P = 0.15

Events by group

Neuraxial vs No neuraxial
OR 0.49 (95 % CI 0.237–1.12); P = 0.15

Observational data: associations, not effects.

Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.

Original publication

Criteria for continuous neuraxial analgesia associated with reduced mortality in patients undergoing thoracotomy. Reg Anesth Pain Med. Published 17 August 2024. doi:10.1136/rapm-2024-105537

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