Critical care outcomes in decompensated cirrhosis: a United States national inpatient sample cross-sectional study
Authors' conclusion
One-third of patients with cirrhosis requiring critical care did not survive to discharge in this U.S. nationwide assessment. While outcomes were worse than in patients without cirrhosis, the results do suggest better outcomes compared to previous studies.
Study context
- Population
- US adults with decompensated cirrhosis requiring intubation and/or central venous catheter, 2016–2019
- Exposure
- Cirrhosis vs Without cirrhosis
- Cirrhosisn = 12,945
- Outcome
- In-hospital mortality
Methodological detailsNational Inpatient Sample 2016–2019
- National Inpatient Sample 2016–2019
Main finding
As reported in the abstract
P < 0.001
Observational data: associations, not effects.
Further findings
Mortality with RRT (RRT used n = 1580, 12.2%)
P < 0.001
Mortality with CPR
P < 0.001
Male sex
P < 0.001
Age
P < 0.001
Mortality with RRT (RRT used n = 1580, 12.2%)
- Lowest in esophageal variceal hemorrhage (EVH) (25.7%), highest in hepatorenal syndrome (HRS) (51.5%)
Mortality with CPR
- Highest in HRS (95.7%)
Original publication
Critical care outcomes in decompensated cirrhosis: a United States national inpatient sample cross-sectional study. Crit Care. Published 7 May 2024. doi:10.
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