Veno-venous extracorporeal membrane oxygenation as a bridge in central airway obstruction: experience from a high-volume center
Authors' conclusion
The application of V-V ECMO with minimal anticoagulation demonstrates safety and efficacy as a bridging support in the therapeutic approach to CAO.
Study context
- Population
- Patients with central airway obstruction (CAO) receiving V–V ECMO support, 2015–2023
- Participants
- 29 consecutive patients
- Outcome
- Survival
- Follow-up
- 6 months
Methodological detailssingle-centre, consecutive patients
- Single-centre
- Consecutive patients
Main finding
As reported in the abstract
- All patients survived through 6-month follow-up
Observational data: associations, not effects.
Further findings
Baseline airway diameter
- Median airway diameter, mm (IQR 2-5 mm)
- 4.5
Etiology of CAO
- Primary tumors
- 17
- Metastases
- 7
- Post-intubation/tracheostomy stenosis
- 5
Treatment
- Bronchoscopic interventions
- 9
- Thoracic surgical procedures
- 15
- Head/neck surgical procedures
- 5
- Femoral-jugular cannulation
- 27
- Minimal anticoagulation protocol (catheter flush with 5U/mL heparin only)
Safety
- Minimal ECMO-related complications
Original publication
Veno-venous extracorporeal membrane oxygenation as a bridge in central airway obstruction: experience from a high-volume center. Crit Care. Published 20 December 2024. doi:10. 1186/ s13054-024-05219-0
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