Critical Illness-Associated Hyperglycemia and New-Onset Diabetes: A Retrospective Cohort Study
Authors' conclusion
CIAH in ICU patients without pre-existing diabetes or prediabetes was associated with a higher risk of developing incident diabetes within 5 years of ICU discharge.
Study context
- Population
- ICU survivors without pre-existing diabetes or prediabetes (no National Diabetes Register (NDR) diagnosis, HbA1c <42 mmol/mol [6%]), 4 university hospital ICUs, Stockholm, Sweden, 2010–2021
- Participants
- 6,633 ICU survivors
- Exposure
- Critical illness-associated hyperglycemia (CIAH) vs no CIAH during ICU treatment
- CIAHn = 3,100
- Outcome
- 5-year cumulative diabetes incidence
- Follow-up
- 5 years
Methodological detailsmulticentre
- Multicentre
Main finding
As reported in the abstract
CIAH vs No CIAHEstimate (95% CI)
Multivariable Cox regression
aHR 2.15(1.52–3.03)
Multivariable competing risk analysis
adjusted sub-hazard ratio 2.20(1.57–3.08)
Observational data: associations, not effects.
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Critical Illness-Associated Hyperglycemia and New-Onset Diabetes: A Retrospective Cohort Study. Crit Care Med. Published 3 October 2025. doi:10.
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