Glycemic control and blood gas sampling frequency during continuous glucose monitoring in the intensive care unit: A before‐and‐after study
Authors' conclusion
In our cohort of ICU patients with type 2 diabetes receiving liberal glycemic control, CGM showed acceptable accuracy and was associated with a reduction in blood gas sampling frequency without compromising glucose control. Lowest accuracy was observed at glucose values below 10 mmol/L and during the first 48 h of CGM use.
Study context
- Population
- Intensive care unit (ICU) patients with type 2 diabetes managed with liberal glucose control (insulin to target 10–14 mmol/L)483 matched glucose values analysed
- Participants
- 15 vs 105
- Comparison
- Continuous glucose monitoring (CGM) vs pre-CGM control
- CGMn = 15
- Pre-CGM controln = 105reference
- Outcome
- Accuracy of CGM vs blood gas glucose (483 matched values); blood gas sampling frequency
Methodological detailslinear regression adjusted for illness severity
- Linear regression adjusted for illness severity
Main finding
As reported in the abstract
Overall mean absolute relative difference (MARD)
11.5 (95% CI, 10.7-12.3)%
Readings in Clarke zones A and B
99%
Reduction in blood gas sampling frequency associated with CGM use
30%
Further findings
MARD by glucose stratum
- <10 mmol/L
- 15.5%
- 10-14 mmol/L
- 11.1%
- >14 mmol/L
- 11.4%
MARD over time
- First 48 h
- 13.8%
- 48-96 h
- 10.9%
- Beyond 96 h
- 8.9%
Blood gas sampling frequency
- CGM use associated with reduction in blood gas sampling frequency
- 30%
- Adjusted for illness severity
Glucose variability (glycemic lability index, SD of blood glucose)
- CGM use not associated with glucose variability
Original publication
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