Hemodynamics, fluids & transfusion
Decision support guided fluid challenges and stroke volume response during high-risk surgery: a post hoc analysis of a randomized controlled trial
Authors' conclusion
AFM-initiated fluid challenges were more often associated with the desired increase in SV than were clinician-initiated fluid challenges, and absolute SV increases were greater.
Study context
- Population
- Patients undergoing high-risk abdominal surgery; fluid challenges of 250-mL crystalloid or albumin boluses over 5 min85 analysed
- Participants
- 86 patients
- Comparison
- Assisted Fluid Management (AFM)-guided vs clinician-initiated fluid challenges
- AFMn = 44
- Controln = 42reference
- Primary endpoint
- Rate of fluid responsiveness (increase in stroke volume (SV) of ≥ 10%) after fluid challenge
Methodological detailspost hoc analysis
- Post hoc analysis
Primary result
As reported in the abstract
Fluid responsiveness rate
P < 0.001
Further findings
Mean SV increase after fluid challenge
P < 0.001
Original publication
Decision support guided fluid challenges and stroke volume response during high-risk surgery: a post hoc analysis of a randomized controlled trial. J Clin Monit Comput. Published 18 January 2025. doi:10.
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