Respiratory failure & ventilation
Declining Use of Prone Positioning After High Initial Uptake in COVID-19 Adult Respiratory Distress Syndrome*
Authors' conclusion
The use of prone positioning for COVID-19 ARDS is declining.
Study context
- Population
- Adults with COVID-19 acute respiratory distress syndrome (ARDS) on invasive mechanical ventilation, PaO2/FiO2 ≤150 mm Hg on FiO2 ≥0.6 within 72 hours of intubation; Five-hospital health system in Maryland, USA, March 2020 to December 202253% severe ARDS
- Participants
- 656 adults
- Exposure
- Proning use by year: 2021 and 2022 vs 2020
- 2020n = 341reference
- 2021n = 224
- 2022n = 91
- Outcome
- Initiation of proning within 48 hours of meeting criteria
- Follow-up
- 48 hours
Methodological detailsmulticentre, observational
- Multicentre
- Observational
Main finding
As reported in the abstract
Early proning
2022 vs 2020Estimate (95% CI)P value
51% reduction
RR 0.49(0.33–0.72)
P < 0.001Early proning
adjusted RR 0.59(0.42–0.82)
P = 0.002Observational data: associations, not effects.
Further findings
Proning use with treatment during COVID-19 surge periods
| Adjusted RR (95% CI) | P value | ||
|---|---|---|---|
| Surge period7% increase | 1.07 (1.02–1.13) | P = 0.01 | |
| 0.512Adjusted relative risk (log scale) |
Original publication
Declining Use of Prone Positioning After High Initial Uptake in COVID-19 Adult Respiratory Distress Syndrome*. Crit Care Med. Published 9 June 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →