Anesthetic drugs & techniques

Deep learning models using intracranial and scalp EEG for predicting sedation level during emergence from anaesthesia

BJA OpenPublished Diagnostic accuracy study

Authors' conclusion

The combination of iEEG and scalp EEG better predicted sedation level than either modality alone.

Study context

Population
Patients emerging from anaesthesia after placement of intracranial electrodes for medically refractory epilepsyplus 5 validation patients
Participants
seven patients
Comparison
Combined vs iEEG only vs Scalp EEG only
Outcome
AUC for predicting OAA/S score 0-2 vs 3-5
Methodological detailsdeep learning model, independent validation cohort
  • Deep learning model
  • Independent validation cohort

Performance

As reported in the abstract

Prediction of OAA/S 0-2 vs 3-5
Test or modelAUCP
Combined0.795P<0.001
iEEG only0.750P=0.02
Scalp EEG only0.764P<0.001

AUC

Combined0.795
iEEG only0.750
Scalp EEG only0.764

P

CombinedP<0.001
iEEG onlyP=0.02
Scalp EEG onlyP<0.001

Further findings

Independent validation, scalp EEG only (5 patients)
0.844 · AUC

Original publication

Deep learning models using intracranial and scalp EEG for predicting sedation level during emergence from anaesthesia. BJA Open. Published 12 October 2024. doi:10.1016/j.bjao.2024.100347

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