Cardiothoracic & vascular anesthesia

Deep Parasternal Intercostal Plane Block for Postoperative Analgesia After Sternotomy for Cardiac Surgery—A Retrospective Cohort Study

J Cardiothorac Vasc AnesthPublished Retrospective cohort study

Main finding · Cumulative opioid consumptionResult — go to the resultEstimated multiplicative change 0.42 95% CI 0.32–0.56

Authors' conclusion

The use of DPIP blocks in patients undergoing cardiac surgery via median sternotomy was associated with less opioid use and improved pain scores in the early postoperative period compared with patients not receiving blocks.

Study context

Population
Adults having elective cardiac surgery via median sternotomy, large quaternary referral center, January 1, 2016, to August 14, 2020matched cohort
Participants
113 vs 3,461
Exposure
Bilateral deep parasternal intercostal plane (DPIP) blocks vs no DPIP block
  • DPIP blockn = 113
  • No DPIP blockn = 3,461reference
Outcome
Cumulative opioid consumption
Follow-up
24 hours
Methodological detailssingle-centre, matched cohort
  • Single-centre
  • Matched cohort

Main finding

As reported in the abstract

Estimated multiplicative change

0.42

95% CI 0.32–0.56

P < 0.001

DPIP block vs No DPIP block
estimated multiplicative change 0.42 (95% CI 0.32–0.56); P < 0.001

Observational data: associations, not effects.

Further findings

OutcomeDPIP blockNo DPIP blockInverse probability of treatment weighting OR (95% CI)P value
Atrial fibrillation incidence (exploratory analysis)Exploratory analysis2%15%0.088 (0.02–0.41)P = 0.002

Average pain score, postoperative day (POD) 0

Proportional OR for average pain score, lower with blocks
0.46 (95% CI 0.32-0.65; p < 0.001)

Average pain score, POD 1

Proportional OR for average pain score, lower with blocks
0.67 (95% CI 0.47-0.94; p = 0.021)

Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.

Original publication

Deep Parasternal Intercostal Plane Block for Postoperative Analgesia After Sternotomy for Cardiac Surgery—A Retrospective Cohort Study. J Cardiothorac Vasc Anesth. Published 4 October 2023. doi:10.1053/j.jvca.2023.09.044

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