Respiratory failure & ventilation
The depth of neuromuscular blockade is not related to chest wall elastance and respiratory mechanics in moderate to severe acute respiratory distress syndrome patients. A prospective cohort study
Authors' conclusion
In ARDS, the relaxation of the respiratory muscles seems to be independent of the NMB level.
Study context
- Population
- Moderate to severe ARDS patientseach analysed at both neuromuscular blockade (NMB) levels
- Participants
- 33 participants
- Exposure
- Deep NMB vs intermediate NMB
- Outcome
- Chest wall elastance (ELCW) according to NMB level
Methodological detailswithin-patient comparison
- Within-patient comparison
Main finding
As reported in the abstract
Chest wall elastance (ELCW)
P = 0.36
Observational data: associations, not effects.
Further findings
Inspiratory oesophageal pressure (Pesinsp)
P = 0.12
| Outcome | TOFC = 0 | TOFC >0 | P value |
|---|---|---|---|
| Expiratory oesophageal pressure (Pesexp) | 8 (range 5–9.5) cmH2O | — not stated in the abstract | P = 0.16 |
— not stated in the abstract
Original publication
The depth of neuromuscular blockade is not related to chest wall elastance and respiratory mechanics in moderate to severe acute respiratory distress syndrome patients. A prospective cohort study. J Crit Care. Published 22 December 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →