Pediatric anesthesia & critical care
Descriptive statistics and risk factor analysis of children with community-acquired septic shock
Authors' conclusion
Children with community-acquired septic shock had high mortality, and early death was common.
Study context
- Population
- Children (age < 20 years) admitted to acute-care hospitals in Japan with sepsis, treated with antibiotics and vasoactive drugs within 3 days of hospitalization, July 2010–March 2020
- Participants
- 761 eligible children
- Outcome
- In-hospital mortality, timing of death and risk factors for earlier death
Methodological detailsnational inpatient database, Cox proportional-hazards regression
- National inpatient database
- Cox proportional-hazards regression
Main finding
As reported in the abstract
In-hospital mortality
Children
32.1%
244 events
- Died on the first day
- 77 (31.6%)
- Died within 3 days of hospitalization
- 156 (63.9%)
Observational data: associations, not effects.
Further findings
| Outcome | Values |
|---|---|
| Discharge with comorbidities among survivors | Survivors 34.4% |
- Discharge with comorbidities among survivors: 517 survivors
Original publication
Descriptive statistics and risk factor analysis of children with community-acquired septic shock. J Intensive Care. Published 13 February 2023. doi:10.
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