Pediatric anesthesia & critical care

A contemporary overview of severe community-acquired bacterial infections in pediatric intensive care units

Ann Intensive CarePublished Prospective cohort study

Authors' conclusion

Severe CABIs in French PICUs in 2024 were mainly caused by B. pertussis and M. pneumoniae, followed by S. pneumoniae and S. aureus. Mortality and morbidity of these infections remain substantial.

Study context

Population
Children with suspected community-acquired bacterial infections admitted to 28 French pediatric intensive care units (PICUs), January–December 2024
Participants
897 children · 28 French PICUs
Outcome
Mortality
Follow-up
Day 28
Methodological detailsmulticenter
  • Multicenter

Main finding

As reported in the abstract

Overall mortality

7%

Mortality with septic shock

19%

Observational data: associations, not effects.

Secondary outcomes

Sequelae among survivors · day 28

Sequelae in survivors
15%

Pathogens identified

Pathogen identified
89%
Bordetella pertussis
22%
Mycoplasma pneumoniae
15%
Streptococcus pneumoniae
13%
Staphylococcus aureus
11%
Viral co-infection
34%

Infection types and severity

Lower respiratory tract infection
43%
Meningitis
20%
Ear-nose-throat infections
13%
Septic shock
17%
Organ support required
70%

Original publication

A contemporary overview of severe community-acquired bacterial infections in pediatric intensive care units. Ann Intensive Care. Published 9 July 2026. doi:10.1016/j.aicoj.2026.100112

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