Pediatric anesthesia & critical care
Detection of Nociceptive Stimuli Using the Newborn Infant Parasympathetic Evaluation Index in Children Aged From 3 to 18 Years
Authors' conclusion
The NIPE index detects the stress response to endotracheal suctioning in children older than 3 years and is more sensitive than hemodynamic parameters, regardless of catecholamine therapy.
Study context
- Population
- Children aged 3–18 years with airway secured by endotracheal intubation or tracheostomy, Motol University Hospital, Prague
- Exposure
- Newborn Infant Parasympathetic Evaluation (NIPE) before, during and 5 min after endotracheal suctioning; NIPE vs haemodynamic parameters
- Outcome
- NIPE value before endotracheal suctioning, 1 min after the start, and 5 min after the end of suctioning
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
NIPE value during endotracheal suctioning
Significantly lower during suctioning; average reduction (100-point scale)
13.4 points
Observational data: associations, not effects.
Further findings
Haemodynamic parameters (heart rate and BP)
- No significant changes, in the whole group or in those not receiving catecholamine support
Original publication
Detection of Nociceptive Stimuli Using the Newborn Infant Parasympathetic Evaluation Index in Children Aged From 3 to 18 Years. Paediatr Anaesth. Published 9 June 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →