Pediatric anesthesia & critical care
The Newborn Infant Parasympathetic Evaluation Index for Assessment of Procedural Pain and Discomfort in Mechanically Ventilated Pediatric Intensive Care Patients: A Prospective, Exploratory, Observational Study
Authors' conclusion
The NIPE detects procedural pain and discomfort in conscious mechanically ventilated infants with an accuracy comparable to established clinical scoring systems.
Study context
- Population
- Conscious mechanically ventilated pediatric intensive care unit (PICU) infants undergoing painful or stressful proceduresmean age 1.2 months
- Participants
- 17 participants
- Exposure
- Newborn Infant Parasympathetic Evaluation (NIPE) values during positive vs negative FLACC and/or COMFORT-B scores
- Outcome
- Performance of NIPE as an indicator of procedural pain and/or discomfort vs FLACC and COMFORT-B
Methodological detailsexploratory
- Exploratory
Main finding
As reported in the abstract
NIPE values
Logistic regression OR range
0.84 and 0.85
ROC AUC range
0.83 and 0.88
Observational data: associations, not effects.
Further findings
NIPE data recording failure
- Periods with FLACC ≥ 4
- 49.3%
- Periods with COMFORT-B ≥ 17
- 40.7%
Original publication
The Newborn Infant Parasympathetic Evaluation Index for Assessment of Procedural Pain and Discomfort in Mechanically Ventilated Pediatric Intensive Care Patients: A Prospective, Exploratory, Observational Study. Paediatr Anaesth. Published 7 December 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →