Detection of Postpartum Hemorrhage Using Compensatory Reserve Index in Patients Undergoing Cesarean Delivery
Main finding · Postdelivery CRIResult — go to the resultDifference −0.13 95% CI −0.13 to −0.12Authors' conclusion
CRI detects changes in central volume status not distinguished by MAP.
Study context
- Population
- Parturients undergoing cesarean delivery
- Participants
- 51 participants
- Exposure
- PPH vs non-PPH
- PPHn = 13
- Outcome
- Trends in CRI between groups
- Follow-up
- 10 to 60-minute window after delivery
Methodological detailsfunction-on-scalar regression, Enrolled February 2020 to May 2021
- Function-on-scalar regression
- Enrolled February 2020 to May 2021
Main finding
Postdelivery CRI · 10 to 60 min after delivery
Difference
−0.13
95% CI −0.13 to −0.12
P < 0.001
PPH vs non-PPH
difference −0.13 (95% CI −0.13 to −0.12); P < 0.001
As reported in the abstract
Observational data: associations, not effects.
Further findings
Average mean arterial pressure (MAP) · 10 to 60 min after delivery
- Average MAP difference, not statistically significant
- −1.67; 95% CI, −3.57 to 0.22; P = .09
Postdelivery compensatory reserve index (CRI) adjusted for preeclampsia and uterotonics
- Lower CRI with PPH persisted after adjustment
Postdelivery CRI, excluding preeclamptics (subanalysis)
- CRI remained lower in those who hemorrhaged
- −0.18; 95% CI, −0.19 to −0.17; P < .001
Postdelivery CRI, excluding GA (subanalysis)
- Similar trends
Original publication
Detection of Postpartum Hemorrhage Using Compensatory Reserve Index in Patients Undergoing Cesarean Delivery. Anesth Analg. Published 8 August 2023. doi:10.
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