Pediatric anesthesia & critical care
Determination of reference ranges for the ClotPro® thromboelastometry device in paediatric patients
Authors' conclusion
ClotPro® reference ranges were determined for six paediatric age groups, and show age-dependent differences in specific parameters.
Study context
- Population
- Children undergoing elective surgery; venous samples after induction of anaesthesia
- Participants
- 321 children
- Exposure
- Six paediatric age groups
- Outcome
- ClotPro® reference ranges (2.5% and 97.5% percentiles) per age group
Methodological detailsreference range determination
- Reference range determination
Main finding
As reported in the abstract
ClotPro® parameters by age group
- EX-test clotting time (CT) significantly shorter at 0-3 months vs all older age groups
- P<0.001
- EX-test and IN-test A5 and A10 significantly higher in first year of life vs children >1 yr
- P<0.001
- FIB-test A5 and A10 significantly higher in first 3 months of life
- P<0.003
Observational data: associations, not effects.
Original publication
Determination of reference ranges for the ClotPro® thromboelastometry device in paediatric patients. Br J Anaesth. Published 12 November 2022. doi:10.
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