ICU sedation, delirium & recovery

Development and External Validation of a Prediction Model for Quality of Life of ICU Survivors: A Subanalysis of the MONITOR-IC Prospective Cohort Study*

Crit Care MedPublished Prediction model development and external validation study

Authors' conclusion

This study developed and externally validated a prediction model for change in quality of life 1 year after ICU admission.

Study context

Population
ICU survivors ≥16 years old, seven hospitals in the Netherlandsincluded in analysis
Participants
1,804 survivors
Comparison
Academic hospital vs Nonacademic hospitals
  • Academic hospitaln = 1,057
  • Nonacademic hospitalsn = 747
Outcome
Change in quality of life (EuroQol 5D questionnaire)
Follow-up
1 year after ICU admission
Methodological detailssubanalysis of the MONITOR-IC prospective cohort study, multicentre, multivariable linear regression, LASSO variable selection
  • Subanalysis of the MONITOR-IC prospective cohort study
  • Multicentre
  • Multivariable linear regression
  • LASSO variable selection

Performance

As reported in the abstract

Explained variance of change in quality of life

Full model (49 variables), R2

56.6%

Final model (baseline quality of life, admission type, GCS), R2

52.5%

External validation, R2 (good predictive power)

53.2%

Original publication

Development and External Validation of a Prediction Model for Quality of Life of ICU Survivors: A Subanalysis of the MONITOR-IC Prospective Cohort Study*. Crit Care Med. Published 20 February 2023. doi:10.1097/ccm.0000000000005800

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