Pediatric anesthesia & critical care

Development and validation of a prediction model for preoperative anxiety in children aged 2–12 years old

Paediatr AnaesthPublished Prediction model development and validation study

Authors' conclusion

In this study, a clinical prediction model was developed and validated for the first time.

Study context

Population
Children aged 2–12 years undergoing elective surgery under GA
Participants
340 vs 140
Comparison
Derivation vs Validation
  • Derivationn = 340
  • Validationn = 140
Outcome
High preoperative anxiety (modified Yale Preoperative Anxiety Scale score >30)
Methodological detailsbinary logistic regression, bootstrap internal validation, external validation
  • Binary logistic regression
  • Bootstrap internal validation
  • External validation

Performance

As reported in the abstract

Model discrimination
Test or modelAUC
Derivation0.961 (95% CI = 0.943-0.979)
Validation0.896 (95% CI = 0.842-0.950)

AUC

Derivation0.961 (95% CI = 0.943-0.979)
Validation0.896 (95% CI = 0.842-0.950)

Further findings

Predictors in final model

OR (95% CI)
Pharmacological intervention0.008 (0.002–0.025)
Nonpharmacological intervention0.342 (0.104–1.127)
Parental education level0.211 (0.108–0.411)
Parental anxiety6.15 (2.396–15.786)
Only child2.417 (1.065–5.488)
History of surgery3.513 (1.137–10.860)
Age0.692 (0.500–0.957)

Original publication

Development and validation of a prediction model for preoperative anxiety in children aged 2–12 years old. Paediatr Anaesth. Published 11 November 2022. doi:10.1111/pan.14572

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