Hemodynamics, fluids & transfusion

Development of a machine learning model to predict intraoperative transfusion and guide type and screen ordering

J Clin AnesthPublished Prediction model development and validation study

Authors' conclusion

Machine learning approaches are feasible in predicting intraoperative transfusion from preoperative variables and may improve preoperative type and screen ordering practices when incorporated into the electronic health record.

Study context

Population
Adults ≥18 years undergoing non-emergency surgery, 2019–2022, single centrecases 2019 to 2021
Participants
100,813 adults
Comparison
Seven machine learning algorithms predicting intraoperative Red Blood Cell (RBC) transfusion
Outcome
Prediction of intraoperative transfusion, external temporal validation
Methodological detailsmachine learning, retrospective, single-centre, external temporal validation
  • Machine learning
  • Retrospective
  • Single-centre
  • External temporal validation

Performance

As reported in the abstract

Test or modelOverall accuracySensitivity
LightGBM76.1% (95% CI, 75.6-76.5)91.2% (95% CI, 89.8-92.5)

LightGBM

Overall accuracy76.1% (95% CI, 75.6-76.5)
Sensitivity91.2% (95% CI, 89.8-92.5)

Further findings

Intraoperative transfusion incidence, 2019-2021

Intraoperative transfusion
5488 (5.4%)

Predicted type and screen to transfusion ratio with LightGBM-based ordering

Ratio would improve from 8.4 to 5.1

Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.

Original publication

Development of a machine learning model to predict intraoperative transfusion and guide type and screen ordering. J Clin Anesth. Published 27 September 2023. doi:10.1016/j.jclinane.2023.111272

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