Respiratory failure & ventilation

Diagnostic accuracy of lung ultrasound in diagnosis of acute respiratory distress syndrome (ARDS) and identification of focal or non-focal ARDS subphenotypes: a systematic review and meta-analysis

Crit CarePublished Systematic review and meta-analysis of diagnostic accuracy studies

Authors' conclusion

This review confirms the hypothesis that LUS is a reliable method for diagnosing ARDS in adult patients.

Study context

Population
Adults assessed for ARDS diagnosis or focal vs non-focal ARDS subphenotypes11 reports
Participants
2,075 adults
Comparison
Lung ultrasound (LUS) vs thoracic CT or chest radiography as reference
Outcome
Diagnostic accuracy (sensitivity and specificity) of LUS for ARDS diagnosis
Methodological detailsQUADAS-2 quality assessment
  • QUADAS-2 quality assessment

Pooled result

As reported in the abstract

ARDS diagnosis (9 studies)
GroupPooled sensitivityPooled specificity
LUS0.631 (95% CI 0.450-0.782)0.942 (95% CI 0.856-0.978)

LUS

Pooled sensitivity0.631 (95% CI 0.450-0.782)
Pooled specificity0.942 (95% CI 0.856-0.978)

Further pooled results

Focal vs non-focal ARDS subphenotype classification (2 studies)

LUS could accurately differentiate focal vs non-focal ARDS subphenotypes; insufficient data for meta-analysis

Original publication

Diagnostic accuracy of lung ultrasound in diagnosis of ARDS and identification of focal or non-focal ARDS subphenotypes: a systematic review and meta-analysis. Crit Care. Published 8 July 2024. doi:10.1186/s13054-024-04985-1

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