Hemodynamics, fluids & transfusion

Diagnostic accuracy of point-of-care ultrasound for shock: a systematic review and meta-analysis

Crit CarePublished Systematic review and meta-analysis of diagnostic accuracy studies

Authors' conclusion

The identification of the etiology for each type of shock using POCUS was characterized by high sensitivity and positive likelihood ratios, especially for obstructive shock.

Study context

Population
Patients with shock (circulatory failure)
Participants
1,132 patients · 12 studies
Comparison
Point-of-care ultrasound (POCUS) for identifying the etiology of shock
Outcome
Pooled diagnostic accuracy of POCUS for each type of shock
Methodological detailsQUADAS-2 quality assessment, PRISMA, prospectively registered protocol
  • QUADAS-2 quality assessment
  • PRISMA
  • Prospectively registered protocol

Pooled result

As reported in the abstract

Pooled sensitivity and specificity (95% CI)
GroupSensitivitySpecificityPositive likelihood ratio
Obstructive shock0.82 (0.68-0.91)0.98 (0.92-0.99)40 (11-105)
Cardiogenic shock0.78 (0.56-0.91)0.96 (0.92-0.98)— not stated in the abstract
Hypovolemic shock0.90 (0.84-0.94)0.92 (0.88-0.95)— not stated in the abstract
Distributive shock0.79 (0.71-0.85)0.96 (0.91-0.98)— not stated in the abstract

Sensitivity

Obstructive shock0.82 (0.68-0.91)
Cardiogenic shock0.78 (0.56-0.91)
Hypovolemic shock0.90 (0.84-0.94)
Distributive shock0.79 (0.71-0.85)

Specificity

Obstructive shock0.98 (0.92-0.99)
Cardiogenic shock0.96 (0.92-0.98)
Hypovolemic shock0.92 (0.88-0.95)
Distributive shock0.96 (0.91-0.98)

Positive likelihood ratio

Obstructive shock40 (11-105)
Cardiogenic shock— not stated in the abstract
Hypovolemic shock— not stated in the abstract
Distributive shock— not stated in the abstract

— not stated in the abstract

AUC for each type of shock approximately
0.95
Positive likelihood ratios for each type of shock all greater than
10
Negative likelihood ratio for each type of shock approximately
0.2

Original publication

Diagnostic accuracy of point-of-care ultrasound for shock: a systematic review and meta-analysis. Crit Care. Published 25 May 2023. doi:10.1186/s13054-023-04495-6

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