Respiratory failure & ventilation
Diaphragmatic ultrasound and its relationship to breathing effort and load: a prospective observational study
Authors' conclusion
In critical care patients spontaneously breathing under resistive load, diaphragmatic excursion had a weak to moderate correlation with indices of breathing effort and differed between weaning success and failure.
Study context
- Population
- Patients undergoing weaning from mechanical ventilation
- Participants
- 49 patients
- Exposure
- Inspiratory resistive loading vs unassisted SBT
- Outcome
- Relationship between diaphragmatic ultrasound (Dex, Tfdi) and breathing effort (ΔPes, ΔPdi, PTPes), repeated measures correlation
Methodological detailsrepeated measures correlation
- Repeated measures correlation
Main finding
As reported in the abstract
Correlation of diaphragmatic ultrasound with breathing effort indices
- Diaphragmatic excursion (Dex) vs ΔPes, r
- 0.5 (p < 0.001)
- Dex vs ΔPdi, r
- 0.55 (p = < 0.001)
- Dex vs PTPes, r
- 0.32 (p = 0.031)
- Tfdi vs ΔPes, r (no correlation)
- 0.27 (p = 0.052)
- Tfdi vs ΔPdi, r (no correlation)
- 0.2 (p = 0.235)
- Tfdi vs PTPes, r (no correlation)
- 0.24 (p = 0.110)
Observational data: associations, not effects.
Further findings
| Outcome | SBT | IRL | P value |
|---|---|---|---|
| Dex | 1.05 (range 0.7–1.59) | 1.44 (range 0.89–1.96) | P = 0.002 |
| Tfdi | 0.46 ± 0.2 | 0.55 ± 0.32 | P = 0.019 |
| Pes | 6.8 (range 4.6–10.23) | 11.87 (range 7.86–18.32) | P < 0.001 |
| Pdi | 7.94 ± 3.81 | 10.89 ± 6.42 | P < 0.001 |
| PTPes | 97.52 (range 55.96–179.87) | 181.10 (range 108.34–311.7) | P < 0.001 |
Original publication
Diaphragmatic ultrasound and its relationship to breathing effort and load: a prospective observational study. Crit Care. Published 13 May 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →