Respiratory failure & ventilation
Different microcirculatory patterns in patients with COVID-19 and non-COVID-19 ARDS: A multicenter cross-sectional study
Authors' conclusion
Patients with COVID-19 exhibited a distinctive pattern of sublingual microcirculation, mainly characterized by increased vascular density.
Study context
- Population
- Mechanically ventilated patients with ARDS from four ICUs, and healthy volunteersfour ICUs
- Participants
- 62 / 20 / 20
- Exposure
- COVID-19 vs non-COVID-19 ARDS
- COVID-19n = 62
- non-COVID-19 ARDSn = 20
- Healthy volunteersn = 20reference
- Outcome
- Sublingual microcirculation (total vascular density) assessed by videomicroscopy
Methodological detailsmulticentre
- Multicentre
Main finding
As reported in the abstract
Total vascular density
P < 0.001
Observational data: associations, not effects.
Further findings
Proportion of perfused vessels and microvascular flow index
- Less alterations in COVID-19 vs non-COVID-19
Determinants of total vascular density (multivariate linear analysis)
- Independently associated with proportion of perfused vessels, SOFA score, base excess and hematocrit
Original publication
Different microcirculatory patterns in patients with COVID-19 and non-COVID-19 ARDS: A multicenter cross-sectional study. J Crit Care. Published 5 November 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →