Differential Cardiac Responses after Passive Leg Raising
Authors' conclusion
Our findings suggest that in certain preload-responsive patients, PLR can induce a more sustained increase in CI, indicating a possible persistent hemodynamic effect.
Study context
- Population
- Mechanically ventilated post-acute ICU patients during fluid removal before SBTs
- Participants
- 27 participants · 60 passive leg raising (PLR) procedures
- Exposure
- Preload-unresponsive vs Preload-responsive, transient peak vs Preload-responsive, sustained elevation
- Outcome
- Cardiac index (bioreactance) before and after passive leg raising (PLR)
Methodological detailssecondary analysis of the FLOW study
- Secondary analysis of the FLOW study
Main finding
As reported in the abstract
Cardiac index before (t-6) vs after (t9) PLR
CI_t-6 vs CI_t9 (median [IQR])
3.7 [2.6; 4.7] vs 3.3 [2.5; 3.4] mL/min/m²
P = 0.306
Preload-unresponsive · no significant CI change
CI_t-6 vs post-PLR
2.7 [2.5; 3.1] vs 3.3 [2.6; 3.8] mL/min/m² vs L/min/m² (as printed)
P = 0.119
Preload-responsive, transient peak
CI_t-6 vs post-PLR
2.8 [2.3; 2.9] vs 3.3 [2.8; 3.9] L/min/m² vs ml/min/m² (as printed)
P = 0.034
Preload-responsive, sustained elevation
Observational data: associations, not effects.
Original publication
Differential Cardiac Responses after Passive Leg Raising. J Clin Monit Comput. Published 6 June 2024. doi:10.
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