Perioperative medicine & outcomes
Disability after non‐cardiac surgery – patient‐centred outcomes and resource utilisation after non‐cardiac surgery ( PACORUS ): a prospective multicentre cohort study*
Authors' conclusion
One year after non-cardiac surgery, 13% of surviving patients experienced a new onset clinically significant disability. Postoperative complications, even those of low severity, were associated with new onset postoperative disability.
Study context
- Population
- Patients undergoing non-cardiac, non-neurosurgical procedures
- Participants
- 1,081 patients
- Outcome
- New onset clinically significant disability (increase in WHO Disability Assessment Schedule (WHODAS) 2.0 score ≥ 5% points from baseline to a final score ≥ 35%) or death
- Follow-up
- Up to 1 year
Methodological detailsmulticentre
- Multicentre
Main finding
As reported in the abstract
New onset clinically significant disability at 1 year
139 of 1081
12.9%
Observational data: associations, not effects.
Further findings
New onset clinically significant disability · 30 days
- New onset clinically significant disability at 30 days
- 238/1066 (22.3%)
Periprocedural risk and 1-year new onset clinically significant disability
- Periprocedural risk, aOR per percent in American College of Surgeons National Surgical Quality Improvement Program score
- aOR 1.05, 95%CI 1.03-1.07
- Postoperative complications of all grades associated with 1-year new onset clinically significant disability
Social support and 1-year new onset clinically significant disability
- Not associated with social support: moderate social support
- OR 0.87, 95%CI 0.54-1.39
- Not associated with social support: strong social support
- OR 0.76, 95%CI 0.47-1.24
Frailty and 1-year new onset clinically significant disability
- Frailty strongly associated
- aOR 3.97, 95%CI 2.54-6.21
Original publication
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