Perioperative medicine & outcomes
Prevalence of perioperative functional disability using World Health Organization Disability Assessment Schedule (WHODAS) 2.0 and associated adverse outcomes in surgical populations: A systematic review and meta-analysis
Authors' conclusion
Functional disability is prevalent in surgical patients and associated with adverse outcomes.
Study context
- Population
- Adult surgical patients (studies published January 2010 to July 13, 2024)
- Participants
- 9,797 patients · 20 studies
- Outcome
- Prevalence of functional disability (WHODAS 2.0; ≥16% exceeds patient-acceptable levels, ≥25% and ≥35% clinically significant disability) at perioperative time points
Pooled result
As reported in the abstract
Pooled prevalence of functional disability
- Preoperative, WHODAS ≥ 16% (exceeding patient-acceptable levels), 95% CI 23%, 42%
- 32%
- Preoperative, WHODAS ≥ 25% (clinically significant), 95% CI 24%, 45%
- 34%
- Preoperative, WHODAS ≥ 35% (clinically significant), 95% CI 11%, 35%
- 21%
- Postoperative at 6 months, WHODAS ≥ 25%, 95% CI 8%, 23%
- 14%
- Postoperative at 12 months, WHODAS ≥ 25%, 95% CI 14%, 17%
- 15%
Further pooled results
Adverse postoperative outcomes associated with preoperative functional disability
- Preoperative functional disability associated with postoperative delirium, longer LOS, non-home discharge and greater postoperative pain
Original publication
Prevalence of perioperative functional disability using WHODAS 2.0 and associated adverse outcomes in surgical populations: A systematic review and meta-analysis. Anaesth Crit Care Pain Med. Published 26 September 2025. doi:10.
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