Perioperative medicine & outcomes

Disease-free survival after gastrectomy is not influenced by Enhanced Recovery After Surgery (ERAS) adherence

Anaesth Crit Care Pain MedPublished Prespecified substudy of the POWER4 prospective cohort study

Authors' conclusion

In this multicentre cohort, ERAS adherence was not independently associated with long-term DFS after gastrectomy for gastric cancer.

Study context

Population
Patients undergoing elective curative-intent gastrectomy for gastric cancercomplete oncologic follow-up
Participants
368 patients
Comparison
High vs low ERAS adherence
Primary endpoint
DFS (time from surgery to recurrence or death)
Methodological detailsmulticentre
  • Multicentre

Primary result

As reported in the abstract

DFS · median follow-up 1616 days
Kaplan-Meier trend across quartiles
p = 0.05

Further findings

Independent predictors of prognosis

Tumour stage, CKD, ASA ≥ III and total gastrectomy independently predicted prognosis

Original publication

Disease-free survival after gastrectomy is not influenced by ERAS adherence. Anaesth Crit Care Pain Med. Published 30 October 2025. doi:10.1016/j.accpm.2025.101661

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