Pediatric anesthesia & critical care

Early warning for SpO2 decrease by the oxygen reserve index in neonates and small infants

Paediatr AnaesthPublished Diagnostic accuracy study

Authors' conclusion

The ORI provided an early warning time for detecting an impending SpO2 decrease in small infants and neonates in the defined interval in this study.

Study context

Population
Neonates and small infants aged <2 years under GA
Participants
100 neonates
Outcome
Warning time and sensitivity of ORI alarms for detecting impending SpO2 decrease

Performance

As reported in the abstract

Impending SpO2 decrease, entire duration of anesthesia
Test or modelValueSensitivityPPV
Preset oxygen reserve index (ORI) alarmwarning time 84 (IQR 56–102) s55% (95% CI 52%-58%)18% (95% CI 17%-20%)

Preset oxygen reserve index (ORI) alarm

Valuewarning time 84 (IQR 56–102) s
Sensitivity55% (95% CI 52%-58%)
PPV18% (95% CI 17%-20%)

Further findings

OutcomeValues
Impending SpO2 decrease, during anesthesia inductionPreset ORI alarm warning time 63 (IQR 40–82) s · sensitivity 56% (44%-68%) · PPV 27% (95% CI 21%-35%)

Agreement of PaO2 intervals with ORI intervals (54 blood gas analyses)

Poor agreement, kappa
0.00 (95% CI = [−0.18; 0.18])
Weight correlated with correct classification of PaO2 interval by ORI interval
P = 0.0129
Height correlated with correct classification of PaO2 interval by ORI interval
P = 0.0376

Original publication

Early warning for SpO2 decrease by the oxygen reserve index in neonates and small infants. Paediatr Anaesth. Published 8 August 2023. doi:10.1111/pan.14743

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