Perioperative medicine & outcomes
Effect of general anaesthesia with remimazolam versus propofol on postoperative quality of recovery in patients undergoing ambulatory arthroscopic meniscus repair: a randomised clinical trial
Primary result · Total QoR-15 scoreResult — go to the resultMedian difference 3 95% CI 1–5Authors' conclusion
Remimazolam-based total i.v. anaesthesia was associated with small improvements in the quality of recovery; however, the improvement was less than the minimally clinically important difference.
Study context
- Population
- Patients aged 18–65 yr scheduled for ambulatory arthroscopic meniscus repair114 analysed
- Participants
- 120 patients
- Comparison
- Remimazolam vs propofol GA
- Primary endpoint
- QoR-15 score
- Follow-up
- POD1
Primary result
Total QoR-15 score
Median difference
3
95% CI 1–5
P = 0.002
By group
Remimazolam
125
IQR 120–127.5
Propofol
121.5
IQR 119–124
Remimazolam vs Propofol
median difference 3 (95% CI 1–5); P = 0.002
As reported in the abstract
Secondary outcomes
| Outcome | Remimazolam | Propofol | P value |
|---|---|---|---|
| QoR-15 physical independence · POD1 | 8.5 (IQR 8–10) | 8 (IQR 7–9) | P = 0.043 |
| QoR-15 psychological support · POD1 | 17 (IQR 13–17) | 12.5 (IQR 12–14) | P < 0.001 |
| Number of awakenings, first postoperative night | P = 0.042 |
Number of awakenings, first postoperative night
- Fewer awakenings with remimazolam
Safety
| Outcome | P value |
|---|---|
| Hypotension | P = 0.04 |
Hypotension
- Lower incidence of hypotension with remimazolam
Original publication
Effect of general anaesthesia with remimazolam versus propofol on postoperative quality of recovery in patients undergoing ambulatory arthroscopic meniscus repair: a randomised clinical trial. BJA Open. Published 28 October 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →