Perioperative medicine & outcomes
Effect of Goal-Directed Intraoperative Blood Pressure Management on Postoperative Delirium in Older Patients Undergoing Hip Fracture Surgery: A Randomized Controlled Trial
Authors' conclusion
Goal-directed intraoperative blood pressure management did not significantly reduce postoperative delirium in older patients undergoing hip fracture repair surgery under spinal anesthesia.
Study context
- Population
- Older patients (over 65 years) scheduled for elective hip fracture repair surgery under spinal anesthesia
- Participants
- 188 patients
- Comparison
- Goal-directed arterial blood pressure (ABP) management vs control
- Goal-directed ABPn = 94
- Controln = 94reference
- Primary endpoint
- Incidence of postoperative delirium (Confusion Assessment Method (CAM), assessed twice daily)
- Follow-up
- Until hospital discharge
Methodological detailssingle-centre
- Single-centre
Primary result
As reported in the abstract
Each group vs controlRelative risk (95% CI)P value
Goal-directed ABP
0.735(0.478–1.130)
P = 0.162- Goal-directed ABP
- absolute risk reduction 9.6% (95% CI −3.6 to 22.8)
Further findings
Accumulative time under 80% preoperative SBP · significantly shorter in goal-directed ABP group
P < 0.001
Postoperative intensive care unit (ICU) admittance and quality of life (EQ-5D-3L) · 3 months
- No difference between groups
Original publication
Effect of Goal-Directed Intraoperative Blood Pressure Management on Postoperative Delirium in Older Patients Undergoing Hip Fracture Surgery: A Randomized Controlled Trial. Anesth Analg. Published 16 December 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →